Adjuvant effect of enterotoxigenic Escherichia coli (ETEC) double-mutant heat-labile toxin (dmLT) on systemic immunogenicity induced by the CFA/I/II/IV MEFA ETEC vaccine: Dose-related enhancement of antibody responses to seven ETEC adhesins (CFA/I, CS1-CS6)

Double-mutant heat-labile toxin (dmLT, LT(R192G/L211A)) of enterotoxigenic Escherichia coli (ETEC) is an effective mucosal adjuvant. Recent studies have shown that dmLT also exhibits adjuvanticity for antigens administered parenterally. In this study, we subcutaneously (SC) immunized mice with the E...

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Bibliografiske detaljer
Udgivet i:Hum Vaccin Immunother
Main Authors: Seo, Hyesuk, Lu, Ti, Mani, Sachin, Bourgeois, A. Louis, Walker, Richard, Sack, David A., Zhang, Weiping
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2019
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7062417/
https://ncbi.nlm.nih.gov/pubmed/31361177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2019.1649555
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