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Genetic Fusions of a CFA/I/II/IV MEFA (Multiepitope Fusion Antigen) and a Toxoid Fusion of Heat-Stable Toxin (STa) and Heat-Labile Toxin (LT) of Enterotoxigenic Escherichia coli (ETEC) Retain Broad Anti-CFA and Antitoxin Antigenicity

Immunological heterogeneity has long been the major challenge in developing broadly effective vaccines to protect humans and animals against bacterial and viral infections. Enterotoxigenic Escherichia coli (ETEC) strains, the leading bacterial cause of diarrhea in humans, express at least 23 immunol...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ruan, Xiaosai, Sack, David A., Zhang, Weiping
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372207/
https://ncbi.nlm.nih.gov/pubmed/25803825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121623
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