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Genetic Fusions of a CFA/I/II/IV MEFA (Multiepitope Fusion Antigen) and a Toxoid Fusion of Heat-Stable Toxin (STa) and Heat-Labile Toxin (LT) of Enterotoxigenic Escherichia coli (ETEC) Retain Broad Anti-CFA and Antitoxin Antigenicity

Immunological heterogeneity has long been the major challenge in developing broadly effective vaccines to protect humans and animals against bacterial and viral infections. Enterotoxigenic Escherichia coli (ETEC) strains, the leading bacterial cause of diarrhea in humans, express at least 23 immunol...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Ruan, Xiaosai, Sack, David A., Zhang, Weiping
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372207/
https://ncbi.nlm.nih.gov/pubmed/25803825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121623
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