Enterotoxigenic Escherichia coli Adhesin-Toxoid Multiepitope Fusion Antigen CFA/I/II/IV-3xSTa(N12S)-mnLT(G192G/L211A)-Derived Antibodies Inhibit Adherence of Seven Adhesins, Neutralize Enterotoxicity of LT and STa Toxins, and Protect Piglets against Diarrhea

Enterotoxigenic Escherichia coli (ETEC) strains are a leading cause of children's diarrhea and travelers' diarrhea. Vaccines inducing antibodies to broadly inhibit bacterial adherence and to neutralize toxin enterotoxicity are expected to be effective against ETEC-associated diarrhea. 6×Hi...

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Vydáno v:Infect Immun
Hlavní autoři: Nandre, Rahul, Ruan, Xiaosai, Lu, Ti, Duan, Qiangde, Sack, David, Zhang, Weiping
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2018
Témata:
Microbial Immunity and Vaccines
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5820944/
https://ncbi.nlm.nih.gov/pubmed/29263112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00550-17
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