Heat-Labile- and Heat-Stable-Toxoid Fusions (LT(R192G)-STa(P13F)) of Human Enterotoxigenic Escherichia coli Elicit Neutralizing Antitoxin Antibodies

Enterotoxigenic Escherichia coli (ETEC) strains are a major cause of diarrheal disease in humans and animals. Adhesins and enterotoxins, including heat-labile (LT) and heat-stable (STa) toxins, are the key virulence factors. Antigenic adhesin and LT antigens have been used in developing vaccines aga...

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Bibliographic Details
Main Authors: Liu, Mei, Ruan, Xiaosai, Zhang, Chengxian, Lawson, Steve R., Knudsen, David E., Nataro, James P., Robertson, Donald C., Zhang, Weiping
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2011
Subjects:
Microbial Immunity and Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187267/
https://ncbi.nlm.nih.gov/pubmed/21788385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00165-11
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