Toxicity and Immunogenicity of Enterotoxigenic Escherichia coli Heat-Labile and Heat-Stable Toxoid Fusion 3xSTa(A14Q)-LT(S63K/R192G/L211A) in a Murine Model

Diarrhea is the second leading cause of death to young children. Enterotoxigenic Escherichia coli (ETEC) are the most common bacteria causing diarrhea. Adhesins and enterotoxins are the virulence determinants in ETEC diarrhea. Adhesins mediate bacterial attachment and colonization, and enterotoxins...

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Библиографические подробности
Главные авторы: Zhang, Chengxian, Knudsen, David E., Liu, Mei, Robertson, Donald C., Zhang, Weiping
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795625/
https://ncbi.nlm.nih.gov/pubmed/24146989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077386
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