Modified Heat-Stable Toxins (hSTa) of Enterotoxigenic Escherichia coli Lose Toxicity but Display Antigenicity after Being Genetically Fused to Heat-Labile Toxoid LT(R192G)

Enterotoxigenic Escherichia coli (ETEC) strains are a major cause of diarrhea in humans and animals. Heat-stable (STa) and heat-labile (LT) enterotoxins produced by ETEC disrupt fluid homeostasis in host small intestinal epithelial cells and cause fluid and electrolyte hyper-secretion that leads to...

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Detalhes bibliográficos
Main Authors: Liu, Mei, Zhang, Chengxian, Mateo, Kristy, Nataro, James P., Robertson, Donald C., Zhang, Weiping
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202872/
https://ncbi.nlm.nih.gov/pubmed/22069760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins3091146
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