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Chitosan nanoparticle-delivered siRNA reduces CXCR4 expression and sensitizes breast cancer cells to cisplatin

Chemokine (C-X-C motif) receptor 4 (CXCR4) has been reported as a poor prognostic biomarker in human breast cancers, and has been suggested as a promising therapeutic target of breast cancer treatment. The present study aims to investigate the delivery efficiency of siRNA by chitosan into breast can...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Biosci Rep
Hauptverfasser: Yu, Shaonan, Chen, Yan, Li, Xuefeng, Gao, Zhongli, Liu, Guifeng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Portland Press Ltd. 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434078/
https://ncbi.nlm.nih.gov/pubmed/28446538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20170122
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