Hyaluronic acid conjugated nanoparticle delivery of siRNA against TWIST reduces tumor burden and enhances sensitivity to cisplatin in ovarian cancer

TWIST protein is critical to development and is activated in many cancers. TWIST regulates epithelial-mesenchymal transition, and is linked to angiogenesis, metastasis, cancer stem cell phenotype, and drug resistance. The majority of epithelial ovarian cancer (EOC) patients with metastatic disease r...

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Publicado no:Nanomedicine
Main Authors: Shahin, Sophia A., Wang, Ruining, Simargi, Shirleen I., Contreras, Altagracia, Parra, Liliana, Qu, Louise, Wen, Wei, Dellinger, Thanh, Unternaehrer, Juli, Tamanoi, Fuyuhiko, Zink, Jeffrey I., Glackin, Carlotta A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186509/
https://ncbi.nlm.nih.gov/pubmed/29665439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2018.04.008
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