Hyaluronic acid conjugated nanoparticle delivery of siRNA against TWIST reduces tumor burden and enhances sensitivity to cisplatin in ovarian cancer

TWIST protein is critical to development and is activated in many cancers. TWIST regulates epithelial-mesenchymal transition, and is linked to angiogenesis, metastasis, cancer stem cell phenotype, and drug resistance. The majority of epithelial ovarian cancer (EOC) patients with metastatic disease r...

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Bibliografske podrobnosti
izdano v:Nanomedicine
Main Authors: Shahin, Sophia A., Wang, Ruining, Simargi, Shirleen I., Contreras, Altagracia, Parra, Liliana, Qu, Louise, Wen, Wei, Dellinger, Thanh, Unternaehrer, Juli, Tamanoi, Fuyuhiko, Zink, Jeffrey I., Glackin, Carlotta A.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186509/
https://ncbi.nlm.nih.gov/pubmed/29665439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2018.04.008
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