טוען...
Histone deacetylase inhibitor LMK235 attenuates vascular constriction and aortic remodelling in hypertension
Here, we report that LMK235, a class I and histone deacetylase (HDAC6)‐preferential HDAC inhibitor, reduces hypertension via inhibition of vascular contraction and vessel hypertrophy. Angiotensin II‐infusion mice and spontaneously hypertensive rats (SHRs) were used to test the anti‐hypertensive effe...
שמור ב:
| הוצא לאור ב: | J Cell Mol Med |
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| Main Authors: | , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
John Wiley and Sons Inc.
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6433685/ https://ncbi.nlm.nih.gov/pubmed/30734467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14188 |
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