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Salvation of the fallen angel: Reactivating mutant p53
The transcription factor p53 is known as the guardian of the genome for its powerful anti‐tumour capacity. However, mutations of p53 that undermine their protein structure, resulting in loss of tumour suppressor function and gain of oncogenic function, have been implicated in more than half of human...
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| Publicado no: | Br J Pharmacol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6433646/ https://ncbi.nlm.nih.gov/pubmed/30632144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14572 |
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