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Salvation of the fallen angel: Reactivating mutant p53
The transcription factor p53 is known as the guardian of the genome for its powerful anti‐tumour capacity. However, mutations of p53 that undermine their protein structure, resulting in loss of tumour suppressor function and gain of oncogenic function, have been implicated in more than half of human...
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| Pubblicato in: | Br J Pharmacol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6433646/ https://ncbi.nlm.nih.gov/pubmed/30632144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14572 |
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