Enhanced efficacy of histone deacetylase inhibitor panobinostat combined with dual PI3K/mTOR inhibitor BEZ235 against glioblastoma

Glioblastoma multiforme (GBM) is the most common malignant brain tumor in adults. Despite multiple treatment strategies, the prognosis is still poor. This study aimed to evaluate the efficacy of combination treatment of GBM with the histone deacetylase (HDAC) inhibitor panobinostat and dual phosphoi...

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Dettagli Bibliografici
Pubblicato in:Nagoya J Med Sci
Autori principali: Meng, Wei, Wang, Baocheng, Mao, Weiwei, Wang, Jiajia, Zhao, Yang, Li, Qifeng, Zhang, Chenran, Ma, Jie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nagoya University 2019
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Original Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433629/
https://ncbi.nlm.nih.gov/pubmed/30962658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18999/nagjms.81.1.93
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