Enhanced efficacy of histone deacetylase inhibitor panobinostat combined with dual PI3K/mTOR inhibitor BEZ235 against glioblastoma

Glioblastoma multiforme (GBM) is the most common malignant brain tumor in adults. Despite multiple treatment strategies, the prognosis is still poor. This study aimed to evaluate the efficacy of combination treatment of GBM with the histone deacetylase (HDAC) inhibitor panobinostat and dual phosphoi...

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Dades bibliogràfiques
Publicat a:Nagoya J Med Sci
Autors principals: Meng, Wei, Wang, Baocheng, Mao, Weiwei, Wang, Jiajia, Zhao, Yang, Li, Qifeng, Zhang, Chenran, Ma, Jie
Format: Artigo
Idioma:Inglês
Publicat: Nagoya University 2019
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Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433629/
https://ncbi.nlm.nih.gov/pubmed/30962658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18999/nagjms.81.1.93
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