Enhanced efficacy of histone deacetylase inhibitor panobinostat combined with dual PI3K/mTOR inhibitor BEZ235 against glioblastoma

Glioblastoma multiforme (GBM) is the most common malignant brain tumor in adults. Despite multiple treatment strategies, the prognosis is still poor. This study aimed to evaluate the efficacy of combination treatment of GBM with the histone deacetylase (HDAC) inhibitor panobinostat and dual phosphoi...

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Detalhes bibliográficos
Publicado no:Nagoya J Med Sci
Main Authors: Meng, Wei, Wang, Baocheng, Mao, Weiwei, Wang, Jiajia, Zhao, Yang, Li, Qifeng, Zhang, Chenran, Ma, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: Nagoya University 2019
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433629/
https://ncbi.nlm.nih.gov/pubmed/30962658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18999/nagjms.81.1.93
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