Regulation of tumor cell – Microenvironment interaction by the autotaxin-lysophosphatidic acid receptor axis

The lipid mediator lysophosphatidic acid (LPA) in biological fluids is primarily produced by cleavage of lysophospholipids by the lysophospholipase D enzyme Autotaxin (ATX). LPA has been identified and abundantly detected in the culture medium of various cancer cell types, tumor effusates, and ascit...

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Bibliographic Details
Published in:Adv Biol Regul
Main Authors: Tigyi, Gabor J., Yue, Junming, Norman, Derek D., Szabo, Erzsebet, Balogh, Andrea, Balazs, Louisa, Zhao, Guannan, Lee, Sue Chin
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433480/
https://ncbi.nlm.nih.gov/pubmed/30243984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbior.2018.09.008
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