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Role of the autotaxin–lysophosphatidate axis in cancer resistance to chemotherapy and radiotherapy
High expression of autotaxin in cancers is often associated with increased tumor progression, angiogenesis and metastasis. This is explained mainly since autotaxin produces the lipid growth factor, lysophosphatidate (LPA), which stimulates cell division, survival and migration. It has recently becom...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3584168/ https://ncbi.nlm.nih.gov/pubmed/22954454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2012.08.015 |
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