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Role of the autotaxin–lysophosphatidate axis in cancer resistance to chemotherapy and radiotherapy

High expression of autotaxin in cancers is often associated with increased tumor progression, angiogenesis and metastasis. This is explained mainly since autotaxin produces the lipid growth factor, lysophosphatidate (LPA), which stimulates cell division, survival and migration. It has recently becom...

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Bibliografische gegevens
Hoofdauteurs: Brindley, David N., Lin, Fang-Tsyr, Tigyi, Gabor J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584168/
https://ncbi.nlm.nih.gov/pubmed/22954454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2012.08.015
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