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Drug resistance mechanisms in colorectal cancer dissected with cell type-specific dynamic logic models

Genomic features are used as biomarkers of sensitivity to kinase inhibitors used widely to treat human cancer, but effective patient stratification based on these principles remains limited in impact. Insofar as kinase inhibitors interfere with signaling dynamics, and, in turn, signaling dynamics af...

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書誌詳細
出版年:Cancer Res
主要な著者: Eduati, Federica, Doldàn-Martelli, Victoria, Klinger, Bertram, Cokelaer, Thomas, Sieber, Anja, Kogera, Fiona, Dorel, Mathurin, Garnett, Mathew J, Blüthgen, Nils, Saez-Rodriguez, Julio
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433282/
https://ncbi.nlm.nih.gov/pubmed/28381545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-0078
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