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Glycoconjugate synthesis using chemoselective ligation

Chemoselective ligation of carbohydrates and polypeptides was achieved using an adipic acid dihydrazide cross-linker. The reducing end of a carbohydrate is efficiently attached to peptides in two steps, constructing a glycoconjugate in high yield and with high regioselectivity, enabling the producti...

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Dades bibliogràfiques
Publicat a:Org Biomol Chem
Autors principals: Cheng, Shuihong, Wantuch, Paeton L., Kizer, Megan E., Middleton, Dustin R., Wang, Ruitong, DiBello, Mikaela, Li, Mingli, Wang, Xing, Li, Xuebing, Ramachandiran, Vasanthi, Avci, Fikri Y., Zhang, Fuming, Zhang, Xing, Linhardt, Robert J.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6431789/
https://ncbi.nlm.nih.gov/pubmed/30778481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9ob00270g
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