Glycoconjugate synthesis using chemoselective ligation

Chemoselective ligation of carbohydrates and polypeptides was achieved using an adipic acid dihydrazide cross-linker. The reducing end of a carbohydrate is efficiently attached to peptides in two steps, constructing a glycoconjugate in high yield and with high regioselectivity, enabling the producti...

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Vydáno v:Org Biomol Chem
Hlavní autoři: Cheng, Shuihong, Wantuch, Paeton L., Kizer, Megan E., Middleton, Dustin R., Wang, Ruitong, DiBello, Mikaela, Li, Mingli, Wang, Xing, Li, Xuebing, Ramachandiran, Vasanthi, Avci, Fikri Y., Zhang, Fuming, Zhang, Xing, Linhardt, Robert J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6431789/
https://ncbi.nlm.nih.gov/pubmed/30778481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9ob00270g
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