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Glycoconjugate synthesis using chemoselective ligation

Chemoselective ligation of carbohydrates and polypeptides was achieved using an adipic acid dihydrazide cross-linker. The reducing end of a carbohydrate is efficiently attached to peptides in two steps, constructing a glycoconjugate in high yield and with high regioselectivity, enabling the producti...

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Dettagli Bibliografici
Pubblicato in:Org Biomol Chem
Autori principali: Cheng, Shuihong, Wantuch, Paeton L., Kizer, Megan E., Middleton, Dustin R., Wang, Ruitong, DiBello, Mikaela, Li, Mingli, Wang, Xing, Li, Xuebing, Ramachandiran, Vasanthi, Avci, Fikri Y., Zhang, Fuming, Zhang, Xing, Linhardt, Robert J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6431789/
https://ncbi.nlm.nih.gov/pubmed/30778481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9ob00270g
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