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Glycoconjugate synthesis using chemoselective ligation

Chemoselective ligation of carbohydrates and polypeptides was achieved using an adipic acid dihydrazide cross-linker. The reducing end of a carbohydrate is efficiently attached to peptides in two steps, constructing a glycoconjugate in high yield and with high regioselectivity, enabling the producti...

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Detalles Bibliográficos
Publicado en:Org Biomol Chem
Main Authors: Cheng, Shuihong, Wantuch, Paeton L., Kizer, Megan E., Middleton, Dustin R., Wang, Ruitong, DiBello, Mikaela, Li, Mingli, Wang, Xing, Li, Xuebing, Ramachandiran, Vasanthi, Avci, Fikri Y., Zhang, Fuming, Zhang, Xing, Linhardt, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6431789/
https://ncbi.nlm.nih.gov/pubmed/30778481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9ob00270g
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