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A New UPLC-MS/MS Method Validated for Quantification of Jervine in Rat Plasma and the Study of Its Pharmacokinetics in Rats

The aim of this study was to develop an ultraperformance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method to assess the concentration of jervine in rat plasma and its pharmacokinetics. Diazepam was used as internal standard (IS). The chromatographic separation of jervine and IS was...

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Detalhes bibliográficos
Publicado no:J Anal Methods Chem
Main Authors: Chen, Lianguo, Weng, Qinghua, Ma, Jianshe
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6431447/
https://ncbi.nlm.nih.gov/pubmed/30956840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/5163625
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