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Validated UPLC-MS/MS method for quantification of fruquintinib in rat plasma and its application to pharmacokinetic study

A new, simple, and sensitive ultraperformance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method for quantification of fruquintinib was established to assess the pharmacokinetics of fruquintinib in the rat. The internal standard working solution was added to the plasma sample for ext...

詳細記述

保存先:
書誌詳細
出版年:Drug Des Devel Ther
主要な著者: Mei, Yi-Bin, Luo, Shun-Bin, Ye, Ling-Yan, Zhang, Qiang, Guo, Jing, Qiu, Xiang-Jun, Xie, Sai-Li
フォーマット: Artigo
言語:Inglês
出版事項: Dove 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6699497/
https://ncbi.nlm.nih.gov/pubmed/31616134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S199362
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