Validated UPLC-MS/MS method for the quantification of dasatinib in plasma: Application to pharmacokinetic interaction studies with nutraceuticals in Wistar rats

Dasatinib (DAS) is a tyrosine kinase inhibitor (TKI) used in the treatment of chronic myeloid leukemia and in the management of ulcerative colitis (UC). Since some nutraceuticals (e.g. curcumin, olive oil, and cocoa extract) could alter the function of ABC transporters and /or CYP450 enzymes, DAS bi...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS One
मुख्य लेखकों: Maher, Hadir M., Alzoman, Nourah Z., Shehata, Shereen M., Abanmy, Norah O.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2018
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002064/
https://ncbi.nlm.nih.gov/pubmed/29902246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0199208
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