Development and validation of a UPLC-MS/MS method for simultaneous detection of doxorubicin and sorafenib in plasma: Application to pharmacokinetic studies in rats

An ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) was developed for the simultaneous quantitation of doxorubicin (DOX) and sorafenib (SOR) in rat plasma. Chromatographic separation was performed using a reversed-phase column C18 (1.7 μm, 1.0 × 100 mm Acquity UPLC BEH™)...

תיאור מלא

מידע ביבליוגרפי

Principais autores:	Alanoud Altalal, Aliyah Almomen, Musaed Alkholief, Ziyad Binkhathlan, Nourah Z. Alzoman, Aws Alshamsan
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Springer 2023-07-01
סדרה:	Saudi Pharmaceutical Journal
נושאים:	Doxorubicin Sorafenib Co-administration UPLC-MS/MS Pharmacokinetics
גישה מקוונת:	http://www.sciencedirect.com/science/article/pii/S1319016423001512
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!