Carregant...
The ribonuclease PARN controls the levels of specific miRNAs that contribute to p53 regulation
PARN loss-of-function mutations cause a severe form of the hereditary disease dyskeratosis congenita (DC). PARN deficiency affects the stability of non-coding RNAs such as human telomerase RNA (hTR), but these effects do not explain the severe disease in patients. We demonstrate that PARN deficiency...
Guardat en:
| Publicat a: | Mol Cell |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6430647/ https://ncbi.nlm.nih.gov/pubmed/30770239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.01.010 |
| Etiquetes: |
Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|