Antigenicity and Immunogenicity of Differentially Glycosylated Hepatitis C Virus E2 Envelope Proteins Expressed in Mammalian and Insect Cells

The development of a prophylactic vaccine for hepatitis C virus (HCV) remains a global health challenge. Cumulative evidence supports the importance of antibodies targeting the HCV E2 envelope glycoprotein to facilitate viral clearance. However, a significant challenge for a B cell-based vaccine is...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Virol
Egile Nagusiak: Urbanowicz, Richard A., Wang, Ruixue, Schiel, John E., Keck, Zhen-yong, Kerzic, Melissa C., Lau, Patrick, Rangarajan, Sneha, Garagusi, Kyle J., Tan, Lei, Guest, Johnathan D., Ball, Jonathan K., Pierce, Brian G., Mariuzza, Roy A., Foung, Steven K. H., Fuerst, Thomas R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2019
Gaiak:
Vaccines and Antiviral Agents
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6430559/
https://ncbi.nlm.nih.gov/pubmed/30651366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01403-18
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