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Decreased Ambient Oxygen Tension Alters the Expression of Endothelin-1, iNOS and cGMP in Rat Alveolar Macrophages

Background: Hypoxia plays an important role in the vascular tone of pulmonary circulation via the vasculature and parenchymal tissue. Endothelin-1 (ET-1), a potent vasoconstrictive peptide, plays a role in inflammation in mononuclear cells. Nitric oxide synthase (NOS), which generates nitric oxide (...

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Pubblicato in:Int J Med Sci
Autori principali: Chen, I-Chen, Lin, Yu-Tsai, Huang, Jhy-Shrian, Wu, Bin-Nan, Hsu, Jong-Hau, Tan, Mian-Shin, Dai, Zen-Kong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428981/
https://ncbi.nlm.nih.gov/pubmed/30911278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.28353
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