KMUP-1 Ameliorates Ischemia-Induced Cardiomyocyte Apoptosis through the NO–cGMP–MAPK Signaling Pathways

To test whether KMUP-1 (7-[2-[4-(2-chlorophenyl) piperazinyl]ethyl]-1,3-dimethylxanthine) prevents myocardial ischemia-induced apoptosis, we examined KMUP-1-treated H9c2 cells culture. Recent attention has focused on the activation of nitric oxide (NO)-guanosine 3’, 5’cyclic monophosphate (cGMP)-pro...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Lee, Meng-Luen, Sulistyowati, Erna, Hsu, Jong-Hau, Huang, Bo-Yau, Dai, Zen-Kong, Wu, Bin-Nan, Chao, Yu-Ying, Yeh, Jwu-Lai
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6479774/
https://ncbi.nlm.nih.gov/pubmed/30965668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24071376
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