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Large-scale network analysis reveals the sequence space architecture of antibody repertoires

The architecture of mouse and human antibody repertoires is defined by the sequence similarity networks of the clones that compose them. The major principles that define the architecture of antibody repertoires have remained largely unknown. Here, we establish a high-performance computing platform t...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Miho, Enkelejda, Roškar, Rok, Greiff, Victor, Reddy, Sai T.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428871/
https://ncbi.nlm.nih.gov/pubmed/30899025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09278-8
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