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Large-scale network analysis reveals the sequence space architecture of antibody repertoires

The architecture of mouse and human antibody repertoires is defined by the sequence similarity networks of the clones that compose them. The major principles that define the architecture of antibody repertoires have remained largely unknown. Here, we establish a high-performance computing platform t...

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Библиографические подробности
Опубликовано в: :Nat Commun
Главные авторы: Miho, Enkelejda, Roškar, Rok, Greiff, Victor, Reddy, Sai T.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428871/
https://ncbi.nlm.nih.gov/pubmed/30899025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09278-8
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