Quantitative assessment of the robustness of next-generation sequencing of antibody variable gene repertoires from immunized mice

BACKGROUND: Next-generation sequencing (NGS) of antibody variable regions has emerged as a powerful tool in systems immunology by providing quantitative molecular information on polyclonal humoral immune responses. Reproducible and robust information on antibody repertoires is valuable for basic and...

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Detalhes bibliográficos
Publicado no:BMC Immunol
Main Authors: Greiff, Victor, Menzel, Ulrike, Haessler, Ulrike, Cook, Skylar C, Friedensohn, Simon, Khan, Tarik A, Pogson, Mark, Hellmann, Ina, Reddy, Sai T
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233042/
https://ncbi.nlm.nih.gov/pubmed/25318652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-014-0040-5
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