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Accurate and predictive antibody repertoire profiling by molecular amplification fingerprinting
High-throughput antibody repertoire sequencing (Ig-seq) provides quantitative molecular information on humoral immunity. However, Ig-seq is compromised by biases and errors introduced during library preparation and sequencing. By using synthetic antibody spike-in genes, we determined that primer bia...
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| Publicado no: | Sci Adv |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Association for the Advancement of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4795664/ https://ncbi.nlm.nih.gov/pubmed/26998518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1501371 |
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