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A bioinformatic framework for immune repertoire diversity profiling enables detection of immunological status

BACKGROUND: Lymphocyte receptor repertoires are continually shaped throughout the lifetime of an individual in response to environmental and pathogenic exposure. Thus, they may serve as a fingerprint of an individual’s ongoing immunological status (e.g., healthy, infected, vaccinated), with far-reac...

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Detalhes bibliográficos
Publicado no:Genome Med
Main Authors: Greiff, Victor, Bhat, Pooja, Cook, Skylar C., Menzel, Ulrike, Kang, Wenjing, Reddy, Sai T.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489130/
https://ncbi.nlm.nih.gov/pubmed/26140055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-015-0169-8
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