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Endogenous and Exogenous Opioids in Pain

Opioids are the most commonly used and effective analgesic treatments for severe pain, but they have recently come under scrutiny owing to epidemic levels of abuse and overdose. These compounds act on the endogenous opioid system, which comprises four G protein-coupled receptors (mu, delta, kappa, a...

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Detalles Bibliográficos
Publicado en:Annu Rev Neurosci
Main Authors: Corder, Gregory, Castro, Daniel C., Bruchas, Michael R., Scherrer, Grégory
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428583/
https://ncbi.nlm.nih.gov/pubmed/29852083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-neuro-080317-061522
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