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Distinct roles of exogenous opioid agonists and endogenous opioid peptides in the peripheral control of neuropathy-triggered heat pain

Neuropathic pain often results from peripheral nerve damage, which can involve immune response. Local leukocyte-derived opioid peptides or exogenous opioid agonists inhibit neuropathy-induced mechanical hypersensitivity in animal models. Since neuropathic pain can also be augmented by heat, in this...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Labuz, Dominika, Celik, Melih Ö., Zimmer, Andreas, Machelska, Halina
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015056/
https://ncbi.nlm.nih.gov/pubmed/27605249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32799
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