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IL-4 induces M2 macrophages to produce sustained analgesia via opioids

IL-4 is a pleiotropic antiinflammatory cytokine, which can be neuroprotective after nervous system injury. The beneficial actions of IL-4 are thought to result from the blunting of action of inflammatory mediators, such as proinflammatory cytokines. Here, we demonstrate that IL-4 induces M2 macropha...

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Publicat a:JCI Insight
Autors principals: Celik, Melih Ö., Labuz, Dominika, Keye, Jacqueline, Glauben, Rainer, Machelska, Halina
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7101153/
https://ncbi.nlm.nih.gov/pubmed/32102987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.133093
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