Cutaneous nociceptors lack sensitisation, but reveal μ-opioid receptor-mediated reduction in excitability to mechanical stimulation in neuropathy

<p>Abstract</p> <p>Background</p> <p>Peripheral nerve injuries often trigger a hypersensitivity to tactile stimulation. Behavioural studies demonstrated efficient and side effect-free analgesia mediated by opioid receptors on peripheral sensory neurons. However, mechani...

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Detalhes bibliográficos
Main Authors: Schmidt Yvonne, Labuz Dominika, Heppenstall Paul A, Machelska Halina
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publishing 2012-11-01
Colecção:Molecular Pain
Assuntos:
Neuropathic pain
Nociceptors
Mechanical sensitivity
Opioids
Acesso em linha:http://www.molecularpain.com/content/8/1/81
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