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Endogenous and Exogenous Opioids in Pain

Opioids are the most commonly used and effective analgesic treatments for severe pain, but they have recently come under scrutiny owing to epidemic levels of abuse and overdose. These compounds act on the endogenous opioid system, which comprises four G protein-coupled receptors (mu, delta, kappa, a...

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Bibliografske podrobnosti
izdano v:Annu Rev Neurosci
Main Authors: Corder, Gregory, Castro, Daniel C., Bruchas, Michael R., Scherrer, Grégory
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428583/
https://ncbi.nlm.nih.gov/pubmed/29852083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-neuro-080317-061522
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