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Endogenous and Exogenous Opioids in Pain

Opioids are the most commonly used and effective analgesic treatments for severe pain, but they have recently come under scrutiny owing to epidemic levels of abuse and overdose. These compounds act on the endogenous opioid system, which comprises four G protein-coupled receptors (mu, delta, kappa, a...

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Detalhes bibliográficos
Publicado no:Annu Rev Neurosci
Main Authors: Corder, Gregory, Castro, Daniel C., Bruchas, Michael R., Scherrer, Grégory
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428583/
https://ncbi.nlm.nih.gov/pubmed/29852083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-neuro-080317-061522
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