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Endogenous and Exogenous Opioids in Pain

Opioids are the most commonly used and effective analgesic treatments for severe pain, but they have recently come under scrutiny owing to epidemic levels of abuse and overdose. These compounds act on the endogenous opioid system, which comprises four G protein-coupled receptors (mu, delta, kappa, a...

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Détails bibliographiques
Publié dans:Annu Rev Neurosci
Auteurs principaux: Corder, Gregory, Castro, Daniel C., Bruchas, Michael R., Scherrer, Grégory
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428583/
https://ncbi.nlm.nih.gov/pubmed/29852083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-neuro-080317-061522
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