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Pre-existing antibodies to candidate gene therapy vectors (adeno-associated vector serotypes) in domestic cats
Adeno-associated virus (AAV) vectors represent promising candidates for gene therapy; however, pre-existing neutralizing antibodies (NAb) may reduce AAV vector delivery efficiency. In this study, the presence of AAV NAb was investigated in cats, which serve as a larger and outbred animal model for t...
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| Udgivet i: | PLoS One |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6428272/ https://ncbi.nlm.nih.gov/pubmed/30897117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0212811 |
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