Nalaganje...

Pre-existing antibodies to candidate gene therapy vectors (adeno-associated vector serotypes) in domestic cats

Adeno-associated virus (AAV) vectors represent promising candidates for gene therapy; however, pre-existing neutralizing antibodies (NAb) may reduce AAV vector delivery efficiency. In this study, the presence of AAV NAb was investigated in cats, which serve as a larger and outbred animal model for t...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Li, Pengfei, Boenzli, Eva, Hofmann-Lehmann, Regina, Helfer-Hungerbuehler, A. Katrin
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428272/
https://ncbi.nlm.nih.gov/pubmed/30897117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0212811
Oznake: Označite
Brez oznak, prvi označite!