The transcription factor Rfx7 limits metabolism of NK cells and promotes their maintenance and immunity

Regulatory factor X 7 (Rfx7) is an uncharacterized transcription factor belonging to a family involved in ciliogenesis and immunity. Here we found that deletion of Rfx7 leads to a decrease in natural killer (NK) cell maintenance and immunity in vivo. Genomic approaches showed that Rfx7 coordinated a...

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Bibliografski detalji
Izdano u:Nat Immunol
Glavni autori: Castro, Wilson, Chelbi, Sonia T., Niogret, Charlène, Ramon-Barros, Cristina, Welten, Suzanne P.M., Osterheld, Kevin, Wang, Haiping, Rota, Giorgia, Morgado, Leonor, Vivier, Eric, Raeber, Miro E., Boyman, Onur, Delorenzi, Mauro, Barras, David, Ho, Ping-Chih, Oxenius, Annette, Guarda, Greta
Format: Artigo
Jezik:Inglês
Izdano: 2018
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428260/
https://ncbi.nlm.nih.gov/pubmed/29967452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-018-0144-9
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