The transcription factor Rfx7 limits metabolism of NK cells and promotes their maintenance and immunity

Regulatory factor X 7 (Rfx7) is an uncharacterized transcription factor belonging to a family involved in ciliogenesis and immunity. Here we found that deletion of Rfx7 leads to a decrease in natural killer (NK) cell maintenance and immunity in vivo. Genomic approaches showed that Rfx7 coordinated a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Immunol
Main Authors: Castro, Wilson, Chelbi, Sonia T., Niogret, Charlène, Ramon-Barros, Cristina, Welten, Suzanne P.M., Osterheld, Kevin, Wang, Haiping, Rota, Giorgia, Morgado, Leonor, Vivier, Eric, Raeber, Miro E., Boyman, Onur, Delorenzi, Mauro, Barras, David, Ho, Ping-Chih, Oxenius, Annette, Guarda, Greta
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428260/
https://ncbi.nlm.nih.gov/pubmed/29967452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-018-0144-9
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados