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T Cell Priming by Activated Nlrc5-Deficient Dendritic Cells Is Unaffected despite Partially Reduced MHC Class I Levels

NLRC5, a member of the NOD-like receptor (NLR) protein family, has recently been characterized as the master transcriptional regulator of MHCI molecules in lymphocytes, in which it is highly expressed. However, its role in activated dendritic cells (DCs), which are instrumental to initiate T cell re...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Immunol
Κύριοι συγγραφείς: Rota, Giorgia, Ludigs, Kristina, Siegert, Stefanie, Tardivel, Aubry, Morgado, Leonor, Reith, Walter, De Gassart, Aude, Guarda, Greta
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: AAI 2016
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4797726/
https://ncbi.nlm.nih.gov/pubmed/26944927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502084
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