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T Cell Priming by Activated Nlrc5-Deficient Dendritic Cells Is Unaffected despite Partially Reduced MHC Class I Levels

NLRC5, a member of the NOD-like receptor (NLR) protein family, has recently been characterized as the master transcriptional regulator of MHCI molecules in lymphocytes, in which it is highly expressed. However, its role in activated dendritic cells (DCs), which are instrumental to initiate T cell re...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Rota, Giorgia, Ludigs, Kristina, Siegert, Stefanie, Tardivel, Aubry, Morgado, Leonor, Reith, Walter, De Gassart, Aude, Guarda, Greta
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4797726/
https://ncbi.nlm.nih.gov/pubmed/26944927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502084
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