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T Cell Priming by Activated Nlrc5-Deficient Dendritic Cells Is Unaffected despite Partially Reduced MHC Class I Levels

NLRC5, a member of the NOD-like receptor (NLR) protein family, has recently been characterized as the master transcriptional regulator of MHCI molecules in lymphocytes, in which it is highly expressed. However, its role in activated dendritic cells (DCs), which are instrumental to initiate T cell re...

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Bibliografiske detaljer
Udgivet i:J Immunol
Main Authors: Rota, Giorgia, Ludigs, Kristina, Siegert, Stefanie, Tardivel, Aubry, Morgado, Leonor, Reith, Walter, De Gassart, Aude, Guarda, Greta
Format: Artigo
Sprog:Inglês
Udgivet: AAI 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4797726/
https://ncbi.nlm.nih.gov/pubmed/26944927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502084
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