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Structural and Dynamic Elucidation of a Non-acid PPARγ Partial Agonist: SR1988

Targeting peroxisome proliferator-activated receptor γ (PPARγ) by synthetic compounds has been shown to elicit insulin sensitising properties in type 2 diabetics. Treatment with a class of these compounds, the thiazolidinediones (TZDs), has shown adverse side effects such as weight gain, fluid reten...

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Detalhes bibliográficos
Publicado no:Nucl Receptor Res
Main Authors: Frkic, Rebecca L., Chua, Benjamin S., Shin, Youseung, Pascal, Bruce D., Novick, Scott J., Kamenecka, Theodore M., Griffin, Patrick R., Bruning, John B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428214/
https://ncbi.nlm.nih.gov/pubmed/30906767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.11131/2018/101350
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