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Increased expression of sFlt-1 in in vivo and in vitro models of human placental hypoxia is mediated by HIF-1
Elevated expression of soluble vascular endothelial growth factor receptor-1 (sFlt-1) in preeclampsia plays a major role in the pathogenesis of this serious disorder of human pregnancy. Although reduced placental oxygenation is thought to be involved in the pathogenesis of preeclampsia, it is unclea...
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| Veröffentlicht in: | Am J Physiol Regul Integr Comp Physiol |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6428068/ https://ncbi.nlm.nih.gov/pubmed/16627691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00794.2005 |
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