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Increased expression of sFlt-1 in in vivo and in vitro models of human placental hypoxia is mediated by HIF-1

Elevated expression of soluble vascular endothelial growth factor receptor-1 (sFlt-1) in preeclampsia plays a major role in the pathogenesis of this serious disorder of human pregnancy. Although reduced placental oxygenation is thought to be involved in the pathogenesis of preeclampsia, it is unclea...

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Detalhes bibliográficos
Publicado no:Am J Physiol Regul Integr Comp Physiol
Main Authors: Nevo, Ori, Soleymanlou, Nima, Wu, Yuan, Xu, Jing, Kingdom, John, Many, Ariel, Zamudio, Stacy, Caniggia, Isabella
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428068/
https://ncbi.nlm.nih.gov/pubmed/16627691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00794.2005
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