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Attenuation of VEGFR-2 Expression by sFlt-1 and Low Oxygen in Human Placenta
Vascular endothelial growth factor receptor 2 (VEGFR-2), the primary receptor for VEGF, is crucial for normal endothelial function. sFlt-1, a truncated and soluble form of VEGFR-1 which binds and inhibits VEGF, is increased in preeclampsia and is positively regulated by low oxygen. Here, we investig...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3834253/ https://ncbi.nlm.nih.gov/pubmed/24260556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081176 |
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